Dr. Kai Pinkernell, Chief Medical Officer and Chief Development Officer (CMO&CDO) of Medigene AG will leave the Company's Executive Management Board for personal reasons as of 31 March 2021. Dr. René Goedkoop will assume the role of acting CMO and will be responsible for the continuation of Medigene's clinical projects, primarily driving the finalization of the Phase I part of the ongoing clinical trial with MDG1011 in patients with acute myeloid leukemia or myelodysplastic syndrome. Dr. Goedkoop previously has held several CMO positions in international biopharmaceutical companies such as Sensimed S.A., Lausanne, Switzerland, EryDel S.p.A., Bresso (Milan), Italy, or Pharnext S.A., Paris, France, and has had a lead role already in Medigene's clinical trials as Vice President Clinical Affairs since January 2019. Dr. Pinkernell will continue to support Medigene in an advisory role for six months.