Motif Bio plc (AIM/Nasdaq: MTFB) announces that in furtherance of the previously announced voluntary de-listing from the NASDAQ Capital Market for the Company's American Depository Shares (ADS's), the Company has filed Form 25 with the US Securities and Exchange Commission on the 9 December 2019.

The Company expects that the last trading day on the NASDAQ Capital Market will be on or about 16 December 2019 as previously announced in the RNS issued on the 26 November 2019.

This announcement contains inside information for the purposes of Article 7 of Regulation (EU) 596/2014.

Contact:

Graham Lumsden

Tel: +44 (0)20 3470 0470

Email: ir@motifbio.com

Forward-Looking Statements

When used in this Press Release, the words or phrases 'intends,' 'anticipates,' 'expected to be' or similar expressions are intended to identify 'forward-looking statements' within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements are subject to certain risks and uncertainties including, but not limited to, changes in economic conditions in the Company's market area, changes in policies by regulatory agencies, fluctuations in interest rates, competition that could cause actual results to differ materially from historical earnings and those presently anticipated or projected, and other risks described in the Company's filings with the Securities and Exchange Commission. The Company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date made. The Company advises readers that the factors listed above could affect the Company's financial performance and could cause the Company's actual results for future periods to differ materially from any opinions or statements expressed with respect to future periods in any current statements. The Company does not undertake, and specifically disclaims any obligation, to publicly release the result of any revision which may be made to any forward-looking statements to reflect events or circumstances after the date of such statements or to reflect the occurrence of anticipated or unanticipated events.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply.

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