ITEM 1.01. Entry into a Material Definitive Agreement.
OnMarch 12, 2021 , a wholly owned subsidiary ofOPKO Health, Inc. (the "Company"),Bio-Reference Laboratories, Inc. , aNew Jersey corporation ("BRLI"), and certain of its subsidiaries entered into an amendment (the "Amendment") to that certain Credit Agreement dated as ofNovember 5, 2015 (as amended, the "Credit Agreement"), by and among BRLI, certain of its subsidiaries from time to time party thereto, the lenders from time to time party thereto andJPMorgan Chase Bank, N.A ., as administrative agent for the lenders. Pursuant to the Amendment, letters of credit, including renewals and extensions, may extend past the maturity date for the Credit Agreement, which isNovember 5, 2021 , subject to certain conditions, including the posting of cash collateral. The Amendment additionally incorporates certain new electronic signature requirements applicable to the Credit Agreement. Except as described in this Current Report on Form 8-K, the other terms of the Credit Agreement remain unchanged. The foregoing descriptions of the Credit Agreement and the Amendment are only summaries and are qualified in their entirety by references to the complete text of the Credit Agreement and the Amendment. A copy of the Credit Agreement was filed with the Company's Annual Report on Form 10-K as Exhibit 10.23, filed with theSecurities and Exchange Commission onFebruary 29, 2016 , and incorporated herein by reference. A copy of the Amendment is attached to this Current Report on Form 8-K as Exhibit 10.1 and incorporated herein by reference. ITEM 9.01. Financial Statements and Exhibits. (d) Exhibits Exhibit No. Description 10.1 Amendment No. 12 to Credit Agreement, dated as of
amongBioReference Laboratories, Inc. , certain of
its subsidiaries, and
JPMorgan Chase Bank, N.A . 104 Cover Page Interactive Data File-the cover page
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the Inline XBRL document
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Exhibit Index Exhibit No. Description 10.1 Amendment No. 12 to Credit Agreement, dated as ofMarch 12, 2021 , by and amongBioReference Laboratories, Inc. , certain of its subsidiaries, andJPMorgan Chase Bank, N.A .
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