Pressure BioSciences, Inc. announced the Company's strategic decision to offer up to five exclusive licenses to their patented and powerful UltraShear Technology™? (UltraShear™? or UST™?) platform for the processing of oil-soluble THC concentrates in water into long-term stable, effectively water-soluble, and highly bioavailable nanoemulsions.

THC is an oil-soluble molecule known to be poorly absorbed when ingested. For THC edibles, most consumers report waiting 30-60 minutes for first-effects and 60-90 minutes to reach peak effects. Consumerience following ingestion often leads to additional dosing and overdosed results.

Conversely, smoking/vaping produces first effects immediately and peak effects quickly but are increasingly in disfavor because of associated respiratory health issues. Additionally, commercial interest is burgeoning for infusing beverages and other products with THC, yet high quality methods to do so remain essentially non-existent today. PBIO recently released news related to the powerful attributes of the UltraShear platform.

Consumer testing results confirmed that an UltraShear nanoemulsion THC oral spray delivered first effects in 1-10 minutes (average 3-5 minutes) and peak effects as early as 15 minutes. These first effects are up to 5-fold faster than current non-UltraShear processed THC edibles. Early data from an-ongoing, expanded marketing study using UltraShear-processed THC correlated well with the earlier study results, again showing lightning quick speed to initial effects with UltraShear processed THC edibles; A leading cannabis academic is expected to publish study results of UltraShear-processed CBD in a peer-reviewed journal soon, demonstrating superiority in speed of action and total bioavailability over existing edible products.

UST-processed nanoemulsions have remained stable at room temperature in excess of 24 months. PBI is offering a limited number of 3-year, exclusive, statewide licenses to their patented UltraShear technology platform for preparing THC nanoemulsions. Processing equipment (BaroShear units) will be custom-manufactured for each Licensee.

Each exclusive license will be for a single US state. The Licensee will pay an up-front license fee plus the cost to build the custom BaroShear equipment that will be placed in their facility. The resulting BaroShear equipment will be under a no-cost 3-year lease.

Following the initial lease period, each Licensee will have a first opportunity right to negotiate an extension to their exclusive license. The Company plans to offer a broad-based "lease and license" program for the BaroShear equipment for THC applications on a non-exclusive basis in approximately two years. When available, no BaroShear systems will be offered for THC processing in any state that has already been designated "Exclusive" through the Early Access Program.