RaySearch Laboratories AB (publ) announced that The Royal Marsden NHS Foundation Trust, a specialist cancer center in the UK, will be the first in the world to implement online adaptive radiation therapy (OART) with RaySearch's treatment planning system RayStation and oncology information system RayCare - including the new ARTemis OART solution under development - in combination with the RadixactTreatment Delivery System from Accuray. The Royal Marsden is at the forefront of radiotherapy research in the UK and globally and has been using RayStation for conventional treatment planning since 2016. Due to funding from The Royal Marsden Cancer Charity, the center recently acquired two additional Radixact treatment delivery machines from Accuray with the intention to utilize these machines for OART.

OART uses the daily acquired patient images to optimize the treatment plan by taking into account the changes in the patient's anatomy while the patient is still on the treatment couch. This procedure, which potentially can have significant benefits for the treatment of the patient, puts high demand on the acquired images by the delivery machine and an efficient information flow between the treatment planning system, the oncology information system and the treatment control system. OART uses the daily acquire patient images to optimize the treatment planning plan by taking into account the change in the patient's anatomy while The patient is still on the treatment cush.

This procedure, which potentially will have significant benefits for the treatment planning of the patient, puts highdemand on the acquired images by the delivering machine and an efficient information flow from the treatment planning system, the Oncology information system and thetreatment control system. OART is a collaborative effort between RaySearch and Accuray, aiming to provide an online adaptive solution for clinicians using the RayStation treatment planning system with the Radixact Treatment Delivery System. It will leverage RayStation's capability for automated adaptive replanning, RayCare's powerful clinical workflow management tools, and the Accuray ClearRTTM imaging, to facilitate an optimized solution for online adaptive therapy.

The Royal Marsden in Sutton plans to implement the full ARTemis package, which has also been funded by The Royal Marsden Cancer Charity. ARTemis is currently under development and The Royal Marsden aims to be the first center in the world to regularly perform OART on patients treated on the Radixact System.