The board of directors of Shanghai Henlius Biotech, Inc. announces that: (i) Mr. Qiyu Chen ("Mr. Chen") resigned as the Chairman of the Board, member and the chairman of the Nomination Committee and chairman of the Strategy Committee with effect from 30 November 2021. Mr. Chen will continue to act as a non-executive director and a member of the Strategy Committee of the Company; (ii) Mr. Wenjie Zhang ("Mr. Zhang"), the executive director and Chief Executive Officer of the Company, has been elected as the Chairman of the Board, member and the chairman of the Nomination Committee and chairman of the Strategy Committee with effect from 30 November 2021; (iii) Mr. Zhang resigned as the President of the Company with effect from 30 November 2021; and (iv) Mr. Jun Zhu has been appointed as the President of the Company with effect from 30 November 2021.