Todos Medical Ltd. announced that its Atlanta-area CLIA/CAP-certified clinical laboratory Provista Diagnostics Inc. is now offering saliva-only MonkeyPox testing. The saliva-based samples collected must be stored in the refrigerator within 1 hour of collection and be shipped with cold packs to arrive at the lab within 72 hours of sample collection. The lab has a result turnaround time of 24-48h from the time the sample arrives at the lab.

The sensitivity achieved for the saliva-based MonkeyPox laboratory-developed test (LDT) is 1.2 viral copies per reaction (0.12 copies/ul). The saliva test is intended to be used primarily in suspected cases of MonkeyPox without lesions. In cases where patients with suspected MonkeyPox present with lesions, it is still recommended to test both lesions and saliva to determine whether the lesions contain virus and whether saliva is representative of systemic active infection.

The Company's sales representatives have begun reaching out to school districts in the Atlanta, Georgia area to make them aware of Provista's saliva testing capabilities. The Provista saliva MonkeyPox test is available in all states, with the exception of New York. The Company expects to be able to offer MonkeyPox testing in New York following a late September inspection by the New York Department of Health (NYDOH).

Provista is now also preparing to validate blood testing for MonkeyPox IgM/IgG antibodies, including collection using finger prick collection devices, as well as validating MonkeyPox fecal samples to identify potential viral persistence after resolution of acute MonkeyPox symptoms.