ACTIVE BIOTECH AB Active Biotech announced that two abstracts with preclinical data for tasquinimod in myelofibrosis and myelodysplastic syndrome have been accepted for presentation at the 65th American Society of Hematology Annual Meeting in San Diego, December 9-12, 2023 (ASH 2023). The abstract demonstrating efficacy of tasquinimod in myelofibrosis has been selected for an oral presentation. The accepted abstracts for ASH 2023 were published today, November 2, 2023.
The abstract, entitled Preclinical studies demonstrating efficacy of tasquinimod in models of advanced myeloproliferative neoplasm (MPN) in blastic phase, will be presented as an oral presentation by Dr. Warren Fiskus, PhD, MD Anderson Cancer Center, Texas, USA. The abstract is a result of the collaboration between Active Biotech and Professor Kapil Bhalla´s research group at MD Anderson, which primarily aims to clarify tasquinimod's mechanisms and effects in myelofibrosis. Data to be presented demonstrate efficacy of tasquinimod as monotherapy and in combination with frontline therapies in models of advanced myelofibrosis.
In addition, the abstract entitled Tasquinimod improves erythropoiesis and mitigates bone loss in myelodysplastic mice will be presented as a poster by Dr. Manja Wobus, University Hospital Dresden, Germany. The abstract comes from collaboration with Dr Wobus in Dresden, showing the first evidence for an in vivo effect of tasquinimod in a murine model of MDS, by significantly improving red blood cell counts and decreasing bone loss.
