Althea Group Holdings Limited announced that Ireland's Primary Care Reimbursement Service (`PCRS') has approved Althea CBD12:THC10 for reimbursement in Ireland. In a follow up to the Company's ASX announcement on 20 May 2022, Althea CBD12:THC10 has now been added to the PCRS in the Republic of Ireland, making it free of charge for Irish patients. The Rapid Review Submission for Althea CBD12:THC10 cannabis oil (50 ml), as included in Schedule 1 of the Misuse of Drugs (Prescription and Control of Supply of Cannabis for Medical Use) (Amendment) Regulations 2023, has resulted in the assignment of administrative codes to facilitate access to the product in line with the Misuse of Drugs (Prescription and Control of Supply of Cannabis for Medical Use) Regulations 2019 (as amended) for the specified therapeutic indications below, with an effective date of 1st August 2023: Spasticity associated with multiple sclerosis resistant to all standard therapies and interventions; Intractable nausea and vomiting associated with chemotherapy, despite the use of standard anti-emetic regimes.

The agreed reimbursement price for Althea CBD12:THC10 (50ml) is 327.89, or approximately AUD 540. Multiple sclerosis (MS) is a complex inflammatory disease of the central nervous system (CNS). The onset of the disease is typically between 20 to 40 years of age, and up to 9,000 people live with this chronic condition in Ireland.

Approximately 70% to 80% of adults with cancer experience chemotherapy-induced nausea and vomiting (CINV). CINV remains one of the most distressing symptoms associated with cancer therapy and is associated with decreased adherence to chemotherapy.