Aptinyx Inc. announced James N. Topper, M.D., Ph.D., who is currently a Class II director, is not standing for reelection to the board of directors at the Annual Meeting, and his term will end following the Annual Meeting. In addition, Wilbur H. Gantz III, who is currently chairman of the board and a Class I director, has resigned from the board due to his retirement, effective as of the Annual Meeting. Patrick G. Enright has been appointed to serve as chairman of the board following the effectiveness of Mr. Gantz's resignation.