On December 15, 2023, Aptinyx Inc.?s board of directors authorized and approved a liquidating cash distribution of $6,683,373 (the Liquidating Distribution) to record holders of the Company?s common stock as of the record date of December 15, 2023 (the Record Date). As a result, each holder of record of Company common stock as of the Record Date is entitled to receive a pro rata portion of the Liquidation Distribution, which is equal to $0.0986975 per share. The Liquidating Distribution will be distributed on or about December 29, 2023 and is expected to be paid to beneficial holders of common stock as of the close of business on December 26, 2023.