Item 8.01. Other Events.

Aytu BioPharma, Inc. (the "Company" or "AYTU") is engaged in discussions with various parties regarding potential strategic transactions and potential financing options. From time to time, AYTU receives inbound interest from parties seeking to partner with AYTU on potential strategic transactions. We are also considering steps to address the ongoing liquidity needs of the Company. As of the date of this Current Report on Form 8-K, AYTU is currently in preliminary discussions with certain parties regarding potential strategic transactions and financing options. We cannot provide assurance that any of these discussions will result in a transaction or financing or, if they did, what the ultimate terms of such strategic transactions or financings would be. Equity financings would provide needed liquidity but could also be dilutive to stockholders. A strategic transaction cannot be assured and may not materialize. These preliminary discussions are ongoing and the AYTU board will continue to evaluate strategic possibilities and financing alternatives consistent with its fiduciary duties.

Forward-Looking Statements; Risks and Uncertainties

Cautionary Note Regarding Forward Looking Statements: This Current Report on Form 8-K contains "forward-looking statements," as that term is defined in U.S. Federal and certain foreign securities regulations, including statements regarding Aytu's consideration of potential strategic transactions, Aytu's consideration of potential financings, the consummation or completion of any strategic transaction or financing and the impact such transaction or financing would have on Aytu's liquidity position. Although Aytu's management believes that its expectations are based on reasonable assumptions, these assumptions are subject to various risks and uncertainties and thus Aytu can give no assurance that its expectations will be attained or that actual developments and results will not materially differ from those express or implied by the forward-looking statements. These risks and uncertainties include, but are not limited to: (1) the effects of any potential inquiry by the United States Securities and Exchange Commission ("SEC") with respect to the proposed restatements or Aytu's accounting practices; (2) the timing of Aytu's restatement of its previously issued financial statements and the filing of Aytu's Second Quarter Form 10-Q; and (3) the additional risks and uncertainties detailed from time to time in Aytu's Annual Report on Form 10-K and quarterly reports on Form 10-Q, which include a list of factors that could cause actual operational and financial results to differ from those expected, and in Aytu's press releases and other filings under the Securities Exchange Act of 1934. This communication should be read in conjunction with all the other information included in our most current Annual Report on Form 10-K, in Quarterly Reports filed on Form 10-Q, and in the other reports and documents it files with the SEC. All documents required to be filed with the SEC are available via on the SEC's website at www.sec.gov.

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