Sartorius and BRAIN jointly researching and adapting novel CRISPR Cas-nucleases. The life science group Sartorius and BRAIN Biotech AG are jointly researching and adapting novel CRISPR-Cas genome editing nucleases for specific applications in the field of life sciences. Genome editing enables the targeted and precise insertion, deletion, or modification in the genome of a living organism. Within the research project Sartorius is testing the novel CRISPR-Cas genome editing nucleases on a range of cell lines. Novel CRISPR-Cas genome editing nucleases can be used to modify the genetic material of cells by specifically altering genes, inserting them into the genome or removing them from it. Scientists can use this biotechnological gene editing process, for example, to make plants more resistant to pests and drought or to produce biological fuels. In biopharmaceuticals, the gene scissors could lead to new therapies and thus improve the chances of curing a wide range of diseases such as cancer, neurodegenerative diseases or hereditary diseases.