Cyxone (publ) has reached an important milestone for the drug candidate rabeximod. Recently, the biological target protein for rabeximod was identified, a finding that has now been confirmed in an independent scientific analysis. This important milestone represents a major step forward for the project as the new knowledge contributes to an increased understanding of the drug's mechanism of action and confirms its First-in-Class status.

Rabeximod is an immunomodulatory drug that has shown selectivity for pro-inflammatory macrophages and dendritic cells, which are cells that are central to the disease process in rheumatoid arthritis. Since the discovery of rabeximod in 2003, it has been documented how the drug significantly inhibits key pro-inflammatory processes in these disease-driving cells, but without having a detailed picture of the drug's target protein. The new research results now provide a much more detailed insight into the drug's mechanism of action.