On April 27, 2022, the Board of Directors of First Wave BioPharma, Inc. approved, effective immediately, an increase in the size of the Board from six directors to seven directors and appointed David Hoffman to serve as a member of the Board to fill the newly-created vacancy. Mr. Hoffman will hold this position until the next annual meeting of the Company's stockholders or until his successor is elected and qualified, subject to his earlier resignation or removal.