IceCure Medical Ltd. announced the publication of a study titled "Cryoablation Allows the Ultimate De-escalation of Surgical Therapy for Select Breast Cancer Patients" in the peer-reviewed journal Annals of Surgical Oncology. The independent study, in which ProSense was one of two cryoablation systems analyzed, was overseen and conducted at the Breast Center of Excellence and the Department of Surgery, School of Medicine at Texas Tech University Health Sciences Center by Sonia Y. Khan MD, Jaclyn Cole MD, Zaina Habrawi MD, Michael W. Melkus PhD, and Rakhshanda Layeequr Rahman MD. One patient died one year after cryoablation due torelated causes.

The patient population in this study is similar to the population in IceCure's ongoing ICE3 study, the largest controlled multi-center clinical trial ever performed in the U.S. for liquid nitrogen-based cryoablation of small, low-risk, early-stage malignant breast tumors as an alternative to surgery. Highlights from the article include: Regarding cost of care, the article states: "Clinical trials have determined not only that cryoablation is just as effective as surgical resection for early-stage, low-risk tumors, but that cryoablation also provides a superior alternative when it comes to financial implications". Citing ICE3 as a leading study that makes the case for surgical de-escalation, the article states: Theablative therapies were first entertained as options for women who might not be good surgical candidates or refuse surgery.

"Cryoablation is an excellent option for select patients to avoid general anesthesia, and enjoy a potential cure without surgery through an outpatient procedure with minimal disruption of life." Stated study co-author, Dr. Rakhshanda LayeeQur Rahman.