IceCure Medical Ltd. developer of the ProSense® System, a minimally-invasive cryoablation technology that destroys tumors by freezing as an alternative to surgical tumor removal, now announced that in parallel with the growing adoption of ProSense®, the number of independent, non-sponsored studies of its cryoablation system has significantly increased. In addition to the 12 studies already published in peer reviewed journals and presented in scientific conferences, two IceCure studies, ICE3 and ICESECRET, and 17 independent, non-sponsored studies are ongoing. There are 13 published and ongoing studies for breast cancer.

The remaining studies are focused on fibroadenomas, endometriosis, and malignant or benign tumors of the lung, kidney, and musculoskeletal system. The ICE3 study, which is expected to be finalized in the first quarter of 2024, is the largest U.S.-controlled multicenter clinical trial ever performed for liquid nitrogen-based cryoablation of early-stage breast cancer. Interim results show a 96.91% recurrence free rate, 100% safety, and 100% doctor and patient satisfaction with cosmetic results.

A recently published independent study conducted using ProSense® in Europe to treat early-stage breast cancer produced very similar results, reporting a 96.8% success rate in women with early-stage breast cancer who declined surgery. Another independent study in Europe demonstrated a 93.4% to 96.8% tumor reduction rate in women diagnosed with molecular subtype Luminal-A and Luminal-B tumors who were deemed inoperable for breast cancer.