Item 4.01 Changes in Registrant's Certifying Accountant.

(a) Dismissal of Independent Registered Public Accounting Firm

On March 25, 2022, the Audit Committee of the Board of Directors (the "Audit Committee") of Innoviva, Inc. (the "Company"), dismissed Grant Thornton LLP ("Grant Thornton") as the Company's independent registered public accounting firm, effective immediately.

Grant Thornton's reports on the Company's consolidated financial statements as of and for the fiscal years ended December 31, 2021 and 2020 did not contain any adverse opinion or disclaimer of opinion, nor were they qualified or modified as to uncertainty, audit scope, or accounting principles.

During the fiscal years ended December 31, 2021 and 2020, and the subsequent interim periods through the date of this Current Report, there were no disagreements within the meaning of Item 304(a)(1)(iv) of Regulation S-K and the related instructions between the Company and Grant Thornton on any matters of accounting principles or practices, financial statement disclosure, or auditing scope or procedure which, if not resolved to Grant Thornton's satisfaction, would have caused Grant Thornton to make reference thereto in their reports, and no "reportable events" within the meaning of Item 304(a)(1)(v) of Regulation S-K.

The Company provided Grant Thornton with a copy of the disclosure contained herein, prior to its filing with the Securities and Exchange Commission (the "Commission"), and requested that Grant Thornton furnish a letter addressed to the Commission stating whether or not it agrees with the above statements. A copy of Grant Thornton's letter, dated March 25, 2022, is filed as Exhibit 16.1 to this Form 8-K.

(b) Engagement of New Independent Registered Public Accounting Firm

On March 25, 2022, following an extensive evaluation and competitive process, the Audit Committee appointed Deloitte & Touche LLP ("Deloitte") as the Company's new independent registered public accounting firm for the Company's fiscal year ending December 31, 2022.

During the fiscal years ended December 31, 2021 and 2020 and the subsequent interim periods through March 25, 2022, neither the Company nor anyone on its behalf has consulted with Deloitte with respect to any of the matters or reportable events set forth in Item 304(a)(2)(i) and (ii) of Regulation S-K.

Item 9.01 Financial Statements and Exhibits.





(d) Exhibits.



Exhibit #   Description

  16.1        Letter from Grant Thornton LLP.
104         Cover Page Interactive File (the cover page tags are embedded within the
            Inline XBRL document).

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