On October 17, 2019, Edward D. Wirth, III, M.D., Ph.D., who joined Lineage Cell Therapeutics, Inc. as Chief Medical Officer in March 2019 as a result of the company’s acquisition of Asterias Biotherapeutics, Inc., informed the company that he has decided to resign effective December 15, 2019. Dr. Wirth’s resignation is not due to any disagreement with the company on any matter relating to its operations, policies, or practices. Dr. Wirth intends to pursue a career opportunity with a company in a non-competitive area of cell therapy.