TABLE OF
CONTENTS
1. | OUR MISSION | 1 |
2. | PATIENT CASE STUDY | 3 |
3. | PHYSICIAN TESTIMONIALS | 5 |
4. | PRODUCT SHOWCASE | 7 |
5. | COLLAGEN AND DME (DURABLE MEDICAL EQUIPMENT) DISTRIBUTION | 10 |
6. | RESEARCH & DEVELOPMENT | 11 |
7. | CHAIR MESSAGE | 13 |
8. | CEO MESSAGE | 15 |
9. | DIRECTORS' REPORT | 19 |
10. | LEAD AUDITORS INDEPENDENCE DECLARATION | 48 |
11. | CONSOLIDATED STATEMENT OF PROFIT OR LOSS AND OTHER COMPREHENSIVE INCOME | 49 |
12. | CONSOLIDATED STATEMENT OF FINANCIAL POSITION | 50 |
13. | CONSOLIDATED STATEMENT OF CHANGES IN EQUITY | 51 |
14. | CONSOLIDATED STATEMENT OF CASH FLOWS | 53 |
15. | NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS | 54 |
16. | DIRECTORS' DECLARATION | 101 |
17. | INDEPENDENT AUDITOR'S REPORT | 102 |
18. | INVESTOR INFORMATION | 106 |
19. | CORPORATE DIRECTORY | 109 |
OU
1 | Annual Report 2023 |
R MISSION
Next Science strives to significantly improve patient outcomes, elevate physician efficacy, and create value within the overall healthcare system through relentless innovation and commitment to education and research on biofilm elimination, infection prevention, and treatments for inflammatory diseases.
2 | Annual Report 2023 |
PATIENT CASE
STUDY
Acute Septic Arthritic Knee
Read the full report
by Dr. Jon Minter
The patient, an 81-year-old male presented to the emergency room 11 days post-operatively. He had undergone a revision Total Knee Arthroplasty (TKA) due to an unstable knee and on admission complained of knee pain, mental confusion, atrial fibrillation, elevated liver enzymes, inability to stand, and urinary retention.
Aspiration of the knee was conducted and bacteria known as Klebsiella Pneumonia was found. Investigation into the source of the infection identified the cause as an infected pacemaker. Given the patients severely declining health, the decision was made to use arthroscopic lavage to treat the infection as a temporising measure.
Results
Arthroscopic lavage was performed using one litre of saline and two litres of XPERIENCETM. The patient was placed on an antibiotic regimen and the infected pacemaker was replaced during hospitalisation.
At one year follow up, the patient is fully healed and did not suffer any recurence of knee symptoms.
3 | Annual Report 2023 |
#NEXTSCIENCEHEALS
View the full poster by Dr. Mark Melin
Intervention in Chronic Wound
Part of a 3-patient pilot study, a 76-year-old female patient presented with thrombocytosis from a chronic, non-healing wound that was resistant to other therapies. The wound was appropriately debrided, soaked in hypochlorous acid, BLASTX applied, and covered with foam dressing with compression socks.
Results
The patient was monitored at 8 weeks and 16 weeks for signs of healing. By the 16-week mark, the wound was fully healed.
TREATMENT TIMELINE
BLASTX Initiated | 4-WeekFollow-up | Wound Closed |
11/30/22 | 12/28/22 | 3/23/2023 |
4 | Annual Report 2023 |
Dr. Matthew Regulsky
Podiatric Surgeon
-
I have used this product in probably a million applications and we're seeing really good results using BLASTX powered by the XBIOTM Technology. We have two randomised control trials to show that when you use that, with the Prepare the RepairTM Paradigm, you can have tremendous amount of healing rates. The death rate from any chronic wound is about 30%, diabetic wounds are about 50% because of all of the inflammation and the complexity of the wounds - my own father suffered from a diabetic foot wound and I had to cut off half of my own father's foot. So, I'm passionate about
the evidence, I'm passionate about the science, and I'm passionate about the results."
PHYSICIAN
TESTIMONIALS
5 | Annual Report 2023 |
#NEXTSCIENCEHEALS
Dr. Ravi K. Bashyal
Orthopedic Surgeon
"As a hip and knee replacement surgeon, my most feared post-op complication is infection. Patients undergoing elective and routine hip or knee replacement are at risk for infection, but it is not their expectation that this will occur. Further, if an infection does occur in a hip or knee replacement, it is a serious complication that always requires surgery to address. In even the most benign circumstance, an infected prosthesis requires at least one repeat operation and many weeks of IV antibiotics - more serious cases may require multiple staged operations, each with likely worse functional final outcomes. Anything I can do to prevent this devastating complication from occurring is of great interest to me. Routine use of XPERIENCETM has been shown to dramatically lower this risk, and has been a game changer in my practice. For over the past two years and over 1000 cases, I have had ZERO infections. There is a multifactorial approach to this, but XPERIENCETM is a big part of this formula. I visualise this product as a paradigm shifting gamechanger. If we can educate and inform the surgical community effectively, it has an opportunity to change standard of care practices in surgery. "
6 | Annual Report 2023 |
PRODUCT
SHOWCASE
In April 2021, XPERIENCETM Advanced Surgical Irrigation received FDA clearance to be sold as a medical device in the United States. This non- toxic technology does not need to be rinsed from the surgical site after closure, offering up to five hours of protection as the solution dilutes in the body, helping to prevent surgical site and post-operative infection.
XPERIENCETM is designed for use in virtually every open orthopedic surgical case, with an initial focus on shoulder, hip, knee, trauma and podiatry.
7 | Annual Report 2023 |
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Next Science Ltd. published this content on 03 April 2024 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 05 April 2024 03:54:02 UTC.