On May 14, 2022, Peter Fromen, the Chief Commercial Officer of Pacific Biosciences of California, Inc. notified the Company of his intention to resign, effective as of May 20, 2022, to pursue new opportunities. Mr. Fromen's decision to resign did not result from any disagreement with the Company on any matter relating to the Company's operations, policies or practices. The Company is conducting a search for its next Chief Commercial Officer.

Until a successor is appointed, Christian Henry, Chief Executive Officer and President, will take over the Company's marketing responsibilities, and Chris Seipert, Vice President, Customer Experience, and formerly the Company's Vice President & General Manager – The Americas & EMEA, will take over the Company's sales, service and support responsibilities.