Safeguard Scientifics, Inc. (NYSE:SFE), which builds value in high-growth life sciences and information technology companies, today announced its return to being included in the Russell 2000(R) Index, a leading benchmark of small-cap stocks compiled by the Russell Investment Group, a leading multi-manager investment services firm. The Russell 2000 Index(R) offers access to the small-cap market and reconstitutes its indexes on an annual basis, ranking companies in the United States stock market by market capitalization. Safeguard's current market capitalization is approximately $250 million.

"We are pleased to be included again in the Russell 2000(R) Index and consider it to be an important milestone for Safeguard and our shareholders," stated Peter J. Boni, President and Chief Executive Officer. "Inclusion in the Russell indexes reflects Safeguard's ability to demonstrate successful execution of our business strategy as we continue to build long-term value for our shareholders."

About Safeguard

Safeguard Scientifics, Inc. (NYSE:SFE) builds value in high-growth, revenue-stage information technology and life sciences businesses. We provide growth capital as well as a range of strategic, operational and management resources to our partner companies. Safeguard participates in expansion financings, corporate spin-outs, management buyouts, recapitalizations, industry consolidations and early-stage financings. For more information about Safeguard and its strategy, visit www.safeguard.com.

Forward-Looking and Cautionary Statements

Except for the historical information and discussions contained herein, statements contained in this release may constitute "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Our forward-looking statements are subject to risks and uncertainties. These forward-looking statements that could cause actual results to differ materially, include, among others, managing rapidly changing technologies, limited access to capital, competition, the ability to attract and retain qualified employees, the ability to execute our strategy, the uncertainty of the future performance of our companies, acquisitions and dispositions of companies, the inability to manage growth, compliance with government regulations and legal liabilities, additional financing requirements, labor disputes, the effect of economic conditions in the business sectors in which our companies operate, and other uncertainties described in the Company's filings with the Securities and Exchange Commission. Many of these factors are beyond our ability to predict or control. In addition, as a result of these and other factors, our past financial performance should not be relied on as an indication of future performance. The Company does not assume any obligation to update any forward-looking statements or other information contained in this press release.