Research Abstract
For minimizing both spread of COVID-19 and health hazard caused, there is an urgent need for an effective test that can simultaneously screen the disease and give other diagnostic indications such as disease severity and prognosis. To this end,
The system developed here utilizes a technology termed 'breathomics', which means comprehensive analysis of biological components in exhaled aerosol using mass spectrometry. Its major benefits over other testing techniques are non-invasive nature of aerosol sampling and the wealth of information that can be associated with various biological implications.
For aerosol sample collection,
The multifaceted analysis data delivered by the system include the levels SARS-Cov-2 proteins, other viral proteins, and the host proteins and metabolites involved in inflammatory responses. In addition to giving direct indication of viral infection, results can be used to evaluate the stage and conditions of the disease, to estimate the risk of disease progression, and to predict prognosis and complications. Further studies with additional input may enable prediction of metabolic diseases such as cardiovascular and pulmonary diseases, lifestyle-related diseases, arteriosclerosis, diabetes, cancer, and health management for preventive medicine. As such, we aim to bring closer the future form of personalized and remote healthcare system which we call 'breath medicine'.
*For Research Use Only. Not for use in diagnostic procedures
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