On January 7, 2022, Thermo Fisher Scientific Inc. entered into a new $5.0 billion unsecured five-year revolving credit facility pursuant to a Credit Agreement among the Company, certain Subsidiaries of the Company from time to time party thereto as Designated Borrowers, Bank of America, N.A., as Administrative Agent and a syndicate of lenders from time to time party thereto. The Credit Facility replaces the Company's existing $3.0 billion unsecured five-year revolving credit facility under that certain Credit Agreement dated December 4, 2020, among the Company, certain Subsidiaries of the Company from time to time party thereto as Designated Borrowers, Bank of America, N.A., as Administrative Agent and a syndicate of lenders from time to time party thereto, which terminated upon effectiveness of the Credit Facility. The Credit Facility expires, and any amounts outstanding thereunder will become due and payable, on January 7, 2027, subject to unlimited one-year extensions at the request of the Company and with the consent of the lenders.

The Credit Facility also contains an expansion option permitting the Company to request increases of up to an aggregate additional $1.0 billion from lenders that elect to make such increase available, upon the satisfaction of certain conditions. The proceeds of the Loans under the Credit Facility may be used for working capital purposes, capital expenditures, acquisitions, repurchases of stock, debentures and other securities, the refinancing of present and future debt and other general corporate purposes. The Company expects to limit borrowings under the Credit Facility to amounts that would leave sufficient borrowing capacity under the CP Program so that it could borrow, if needed, to repay all of the outstanding CP Notes as they mature.

If no Default or Event of Default has occurred, (i) each Term SOFR Loan, Alternative Currency Daily Rate Loan, and Alternative Currency Term Rate Loan shall bear interest on the outstanding principal amount thereof for each Interest Period at a variable rate per annum equal to Term SOFR, the relevant Alternative Currency Daily Rate or the relevant Alternative Currency Term Rate, respectively, for such Interest Period plus a margin of 0.795% to 1.300% based on the Company's long-term debt credit ratings and (ii) each Base Rate Committed Loan shall bear interest on the outstanding principal amount thereof from the applicable borrowing date at a variable rate per annum equal to the Base Rate plus a margin of 0.000% to 0.300% based on the Company's long-term debt credit rating. In addition, the Company has agreed to pay a facility fee equal to a variable rate between 0.080% and 0.200% per year based on the Company's long-term debt credit rating times the actual daily amount of the Commitments, regardless of usage, quarterly in arrears on the last business day of each March, June, September and December, commencing with the first such date to occur after the Closing Date.