Item 1.01. Entry into a Material Definitive Agreement.

On June 9, 2022, the Board of Directors (the "Board") of Zymeworks Inc., a corporation continued under the Business Corporations Act (British Columbia) (the "Company"), authorized and declared a dividend distribution of one right (each, a "Right") for each outstanding common share, no par value (the "Common Shares"), of the Company to shareholders of record as of the close of business on June 21, 2022 (the "Record Date"). Each Right entitles the registered holder to purchase from the Company one one-thousandth of a share of Series A Participating Preferred Share, no par value (the "Preferred Shares"), of the Company at an exercise price of $74.00 (the "Exercise Price"), subject to adjustment. The complete terms of the Rights are set forth in a Preferred Shares Rights Agreement (the "Rights Agreement"), dated as of June 9, 2022, between the Company and Computershare Trust Company, N.A., as rights agent.

The Board adopted the Rights Agreement to protect shareholders from coercive or otherwise unfair takeover tactics. In general terms, it works by imposing a significant penalty upon any person or group that acquires 10 percent or more (or 20 percent or more in the case of certain institutional investors who report their holdings on Schedule 13G) of the Common Shares without the approval of the Board. As a result, the overall effect of the Rights Agreement and the issuance of the Rights may be to render more difficult or discourage a merger, amalgamation, arrangement, take-over bid, tender or exchange offer or other business combination involving the Company that is not approved by the Board. However, neither the Rights Agreement nor the Rights should interfere with any merger, amalgamation, arrangement, take-over bid, tender or exchange offer or other business combination approved by the Board.

The following is a summary of the terms of the Rights Agreement. The summary does not purport to be complete and is qualified in its entirety by reference to the Rights Agreement, a copy of which is attached as Exhibit 4.1 and is incorporated herein by reference.



Distribution and       The Board has declared a dividend of one Right for each Common
Transfer of Rights;    Share outstanding. Prior to the Distribution Date referred to
Rights Certificates:   below:

                       • the Rights will be evidenced by and trade with the certificates
                       for Common Shares (or, with respect to any uncertificated Common
                       Shares registered in book entry form, by notation in book entry),
                       and no separate rights certificates will be distributed;

                       • new Common Share certificates issued after the Record Date will
                       contain a legend incorporating the Rights Agreement by reference
                       (for uncertificated Common Shares registered in book entry form,
                       this legend will be contained in a notation in book entry); and

                       • the surrender for transfer of any certificates for Common Shares
                       (or the surrender for transfer of any uncertificated Common Shares
                       registered in book entry form) will also constitute the transfer
                       of the Rights associated with such Common Shares.

                       Rights will accompany any new Common Shares that are issued after
                       the Record Date.

Distribution Date:     Subject to certain exceptions specified in the Rights Agreement,
                       the Rights will separate from the Common Shares and become
                       exercisable following (1) the 10th business day (or such later
                       date as may be determined by the Board) after the public
                       announcement that a person or group of affiliated or associated
                       persons (such person or group, an "Acquiring Person") has acquired
                       beneficial ownership of 10 percent or more (or 20 percent or more
                       in the case of certain institutional investors who report their
                       holdings on Schedule 13G) of the Common Shares or (2) the 10th
                       business day (or such later date as may be determined by the
                       Board) after a person or group announces a tender or exchange
                       offer that would result in ownership by a person or

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                      group of 10 percent or more (or 20 percent or more in the case of
                      certain institutional investors who report their holdings on
                      Schedule 13G) of the Common Shares. For purposes of the Rights
                      Agreement, beneficial ownership is defined to include the ownership
                      of derivative securities.

                      The date on which the Rights separate from the Common Shares and
                      become exercisable is referred to as the "Distribution Date."

                      After the Distribution Date, the Company will mail Rights
                      certificates to the Company's shareholders as of the close of
                      business on the Distribution Date and the Rights will become
                      transferable apart from the Common Shares. Thereafter, such Rights
                      certificates alone will represent the Rights.

Preferred Shares      After the Distribution Date, each Right will entitle the holder to
Purchasable Upon      purchase, for the Exercise Price, one one-thousandth of a Preferred
Exercise of Rights:   Share having economic and other terms similar to that of one Common
. . .

Item 3.03. Material Modification to Rights of Security Holders.

The information included in Item 1.01 and Item 5.03 of this Current Report on Form 8-K is incorporated by reference into this Item 3.03.

Item 5.03. Amendments to Articles of Incorporation or Bylaws; Change in Fiscal


           Year.


The information included in Item 1.01 is incorporated herein by reference.

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In connection with the adoption of the Rights Agreement, on June 9, 2022, the Board approved by resolution an increase to its authorized share structure by creating an unlimited number of Series A Participating Preferred Shares and amending its articles by providing for special rights and restrictions of the Series A Participating Preferred Shares (the "Articles Alteration"). The notice of the Articles Alteration was filed with the office of the Province of British Columbia Registrar of Companies on June 10, 2022. A copy of the resolutions providing for the Articles Alteration is attached as Exhibit 3.1 and is incorporated herein by reference.

Item 8.01. Other Events.

On June 10, 2022, the Company issued a press release announcing the adoption of the Rights Agreement and the declaration of the dividend of Rights ("Press Release"). A copy of the Press Release is attached as Exhibit 99.1 and incorporated herein by reference.

As noted in the Press Release, the Company is subject to both U.S. and Canadian securities laws. Based on information available to the Company, less than 10% of its Common Shares are held by shareholders in Canada. As a result, Canadian securities laws related to the timing of, and process for, any formal offer to acquire control of the Company would not be applicable to such an offer. Instead, any formal offer will be governed by U.S. securities laws.

On June 10, 2022, Zymeworks filed a material change report regarding the adoption of the adoption of the Rights Agreement and the declaration of the dividend of Rights, as described in the Press Release with the Canadian securities regulatory authorities. A copy of this material change report is attached as Exhibit 99.2 hereto.

Item 9.01. Financial Statements and Exhibits.




(d) Exhibits.

Exhibit
  No.                                    Description

 3.1          Resolutions of the Board of Directors of Zymeworks, Inc.
            (incorporated by reference to Exhibit A of Exhibit 4.1 hereto)

 4.1          Preferred Shares Rights Agreement, dated as of June 9, 2022, by and
            between Zymeworks Inc. and Computershare Trust Company, N.A., as
            rights agent.

99.1          Press Release, dated June 10, 2022.

99.2          Material Change Report dated June 10, 2022.

104         Cover Page Interactive Data File (formatted as Inline XBRL).

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