The blue-chip FTSE 100 fell 0.5% while the mid-cap FTSE 250 shed 0.6% by 0827 GMT.

The past week saw the U.S., UK and European Union central banks raise rates as expected and pledge to continue raising rates into the next year.

UK retail sales dropped by 0.4% in November, against expectations of a 0.3% rise from October, highlighting the stress felt by households as a cost-of-living crisis squeezed their finances. Retailers shed 1%.

In company news, gaming operator Rank Group fell 7.8% after warning of a lower full-year profit due to a drop in customer spending amid the cost-of-living crisis.

Drugmakers such as AstraZeneca and industrial firms were also big drags on the FTSE 100.

(Reporting by Johann M Cherian in Bengaluru; Editing by Savio D'Souza)