Valuation: Bicycle Therapeutics plc

Market Cap 255M 227M 210M 191M 357M 24.19B 362M 2.53B 1B 12.66B 956M 936M 39.95B P/E 2026 *
-1.4x
P/E 2027 * -1.56x
Enterprise Value -258M -230M -213M -193M -361M -24.49B -367M -2.56B -1.01B -12.82B -968M -948M -40.46B EV / Sales 2026 *
-14.7x
EV / Sales 2027 * -22.2x
Free-Float
71.25%
Yield 2026 *
-
Yield 2027 * -
1 day-2.47%
1 week-1.39%
Current month-3.53%
1 month-4.83%
3 months-15.68%
6 months-28.86%
Current year-49.86%
1 week 3.41
Extreme 3.41
3.8
1 month 3.33
Extreme 3.3301
4.04
Current year 3.33
Extreme 3.3301
7.34
1 year 3.33
Extreme 3.3301
9.08
3 years 3.33
Extreme 3.3301
28.67
5 years 3.33
Extreme 3.3301
62.08
10 years 3.33
Extreme 3.3301
62.08
Manager TitleAgeSince
Chief Executive Officer 57 2015-08-31
Director of Finance/CFO 46 2026-01-28
Chief Tech/Sci/R&D Officer - 2025-05-31
Director TitleAgeSince
Director/Board Member 57 2015-08-31
Director/Board Member 63 2021-03-16
Director/Board Member 69 2024-02-19
Date Insider Type Main position Quantity % Market Cap. Importance
10/5/26 Sell

Chief Operating Officer

-356 0.0009%
10/5/26 Sell

Chief Operating Officer

-406 0.0011%
10/5/26 Sell

Chief Financial Officer

-79 0.0002%
Change 5-day change 1-year change 3-year change Capi.($)
-2.47%-1.39%-54.95%-79.26% 255M
+2.41%-6.33%+43.43%+71.02% 63.29B
-0.15%+3.11%+10.29%+72.56% 54.89B
+0.57%+4.64%+12.82%+89.79% 53.28B
+0.37%+3.07%+28.23%+51.53% 45.81B
-1.21%+0.95%+20.44%+128.58% 43.46B
-0.37%-1.20%+252.94%+568.54% 40.23B
+0.05%+6.75%+14.48%+56.75% 33.45B
+1.19%-5.84%+27.86%-0.65% 23.7B
-0.38%+4.55%+37.71%+28.10% 23.76B
Average +0.00%+0.41%+39.33%+98.69% 38.21B
Weighted average by Cap. +0.38%+0.55%+48.10%+121.98%

Financials

2026 *2027 *
Net sales 17.53M 15.65M 14.45M 13.11M 24.55M 1.66B 24.93M 174M 68.84M 871M 65.79M 64.39M 2.75B 6.69M 5.97M 5.51M 5M 9.37M 635M 9.51M 66.37M 26.26M 332M 25.1M 24.56M 1.05B
Net income -172M -154M -142M -129M -241M -16.33B -245M -1.71B -676M -8.55B -646M -632M -26.98B -174M -156M -144M -130M -244M -16.56B -248M -1.73B -685M -8.67B -654M -641M -27.35B
Net Debt -513M -458M -423M -383M -718M -48.68B -729M -5.09B -2.01B -25.48B -1.92B -1.88B -80.41B -403M -360M -332M -302M -565M -38.29B -574M -4B -1.58B -20.04B -1.51B -1.48B -63.25B
Projected Income Statement - Annual - Bicycle Therapeutics plc
Logo Bicycle Therapeutics plc
Bicycle Therapeutics plc is a United Kingdom-based clinical-stage biopharmaceutical company developing a class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. The Company is evaluating zelenectide pevedotin, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target, and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in Company-sponsored clinical trials. Additionally, the Company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.
Employees
288
Date Price Change Volume
26-10-23 $3.550 -2.47% 346,807
26-10-22 $3.640 +1.96% 276,237
26-10-21 $3.570 -0.83% 406,403
26-10-20 $3.600 +1.84% 488,210
26-10-19 $3.535 +2.17% 692,062
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
MarketScreener Ratings - Bicycle Therapeutics plc
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
9
Last Close Price
3.640USD
Average target price
9.500USD
Spread / Average Target
+160.99%

Quarterly revenue - Rate of surprise

Rate of surprise - Net sales - Quarterly - Bicycle Therapeutics plc
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