John Wiley & Sons : New Findings on How Diabetes Impacts Bone Health

In addition to causing blood sugar imbalances, type 1 diabetes can contribute to nerve damage and sensory abnormalities-a condition call neuropathy-and has been linked to a higher risk of bone fractures. A new study published in the Journal of Bone and Mineral Research has examined the effects of type 1 diabetes and diabetic neuropathy on the skeleton.

Investigators found that type 1 diabetes and diabetic neuropathy have various impacts on bone structure, but these effects do not fully explain the higher fracture risk in patients with type 1 diabetes.

The results suggest that the increase in the risk of fractures in type 1 diabetes is multifactorial, with both skeletal and non-skeletal features involved.

'It is important to investigate what leads to an increased risk of fractures in type 1 diabetes. Our results suggest that in addition to bone features, balance and muscle strength also play a role,' said lead author Tatiane Vilaca, MD, PhD, of the University of Sheffield, in the U.K. 'These findings could help improve approaches to fracture prevention.'

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/jbmr.4271

About Journal

The Journal of Bone and Mineral Research (JBMR) publishes highly impactful original manuscripts, reviews, and special articles on basic, translational and clinical investigations relevant to the musculoskeletal system and mineral metabolism. Specifically, the journal is interested in original research on the biology and physiology of skeletal tissues, interdisciplinary research spanning the musculoskeletal and other systems, including but not limited to immunology, hematology, energy metabolism, cancer biology, and neurology, and systems biology topics using large scale '-omics' approaches. The journal welcomes clinical research on the pathophysiology, treatment and prevention of osteoporosis and fractures, as well as sarcopenia, disorders of bone and mineral metabolism, and rare or genetically determined bone diseases.

About Wiley

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