On February 27, 2023, Christopher Kirk, Ph.D., President, Chief Scientific Officer and member of the Board of Directors of Kezar Life Sciences, Inc., provided notice of his intention to resign from the positions of President and Chief Scientific Officer of the Company for personal reasons, effective April 21, 2023 (the “Resignation Date”). The Company expects to enter into an advisor agreement with Dr. Kirk pursuant to which Dr. Kirk will serve as a strategic and scientific advisor to the Company following the Resignation Date, which agreement will be described in a future Current Report on Form 8-K to be filed by the Company. Dr. Kirk will remain on the Board, and will receive compensation pursuant to the Company's Non-Employee Director Compensation Policy, following the Resignation Date.