Lexaria Bioscience Corp. informed that its wholly-owned and patented DehydraTECH-CBD formulation, when administered to rodents in an 8-week study (DIAB-A22-1), resulted in weight loss of 7% and a reduction of 19.9% (p<0.05) in blood glucose. Lexaria has now signed contracts to begin animal study WEIGHT-A24-1; (the "Study"), which will be a large, multi-week animal study that will substantially progress its further DehydraTECH-GLP-1 and DehydraTECH- CBD weight loss investigations.

Lexaria also recently published results in a human study, wherein a single 7 mg semaglutide dose from Rybelsus®? processed with DehydraTECH and administered to humans, was absorbed at a significantly higher level than without DehydraTECH processing; and also managed blood glucose levels more effectively without any blood glucose spiking after eating. Together, these discoveries strongly support additional investigations, including: determining whether daily dosing of DehydraTECH- GLP-1 might result in sustained higher concentrations of GLP-1 in blood over an extended treatment duration than without DehydraTech processing; and whether such a higher blood concentration might result in greater weight loss over time, and determining whether DehydraTECH-cBD, specially formulated for diabetes control and weight loss, alone and/or in conjunction with DehydraTECH-GlP-1, might also result in greater weight loss and/or blood glucose control over time.

Manufacturing of the test articles for 8 of the 12 arms of the new animal Study has already been completed, and dosing in those arms will commence as soon as the third-party laboratory is able to do so, expected to begin within 45 days. Four different DehydraTECH-Liraglutide compositions will be tested, as well as 4 different DehydraTech-semaglutide formulas and a single, first ever DehydraTECH-liraglutide composition). The comprehensive Study will also test 1 DehydraTECH-SCBD composition combined with DehydraTECH -semaglutide; and 1 DehydraTech-CBD composition combined with the DehydraTECH- Liraglutide composition.