Orchestra BioMed Holdings, Inc. announced the addition of several highly accomplished industry veterans to its senior leadership team. Avi Fischer, M.D., joins as Senior Vice President (SVP), Medical Affairs and Innovation, and J.C. Simeon assumes the role of SVP, Quality. George Papandreou, Ph.D., has been promoted to SVP of Focal Therapies (previously SVP, Quality).

Dr. Fischer brings to Orchestra BioMed extensive experience in procedural medicine and clinical research, particularly in the areas of electrophysiology and cardiac rhythm management. Most recently, he served as Chief Executive Officer of ElectroPhysiology Frontiers, S.p.A., a privately held medtech company developing a single-shot ablation system to treat atrial fibrillation. Previously, Dr. Fisher worked at St.

Jude Medical and Abbott, where he held various leadership roles including Chief Medical Officer, Cardiac Rhythm Management, and Divisional Vice President, Medical Affairs. For 11 years prior to joining industry, Dr. Fisher was Medical Director, Pacemaker and Defibrillator Therapy, for Mount Sinai Medical Center in New York City. He earned his doctor of medicine degree from Tel Aviv University.

Mr. Simeon has more than two decades of experience in biopharmaceutical quality assurance and engineering as well as expertise in process development, characterization, scale-up, optimization, trouble shooting and technology transfer of manufacturing processes from the laboratory to commercial markets. He previously worked for Amring Pharmaceuticals as Head of Quality Assurance and Regulatory Affairs and was also Executive Director of Quality at Actinium Pharmaceuticals. He earned his bachelor's degree in chemical engineering and his master of science degree in biomedical engineering from the New Jersey Institute of Technology.

Dr. Papandreou has over 25 years of management, R&D, quality and regulatory experience working with transformational drug/device combination products. Prior to joining Orchestra BioMed, he held senior roles at C.R. Bard/Becton Dickinson and Johnson & Johnson (Cordis Corporation).