PacBio announced the commencement of a program intended to expand Multiplexed Arrays Sequencing for new assays on the Sequel II/IIe and Revio sequencing systems. This program builds on the successful MAS-Seq concatenation technology launched last year that enabled cost-effective single-cell isoform sequencing. The MAS-Seq technology concatenates multiple shorter fragments which are then read on the system as one long HiFi read. This extends the effective throughput by up to 16-fold, where the throughput increase factor is determined by the size of the short fragment.

We believe that extending MAS-Seq technology to key applications such as bulk RNA sequencing and 16S rRNA will provide customers with cost-effective kitted solutions and end-to-end software. PacBio intends to launch this first expanded series of MAS-Seq kits in the second half of 2023. PacBio plans to share early data and a technical overview to interested parties at this week's Advances in Genome Biology and Technology (AGBT) General Meeting taking place February 6-9, 2023 in Hollywood, FL.