Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.

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Market Closed - Börse Stuttgart 05:04:00 2026-05-21 am EDT			5-day change	1st Jan Change
0.0100 ^EUR	-.--%		-41.18%	-9.09%

May. 18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
Nov. 17	Adaptimmune Therapeutics plc Announces CEO Changes	CI

Market Cap	7.42M 6.4M 6M 5.47M 10.31M 709M 10.34M 71.14M 27.76M 358M 27.86M 27.26M 1.19B	P/E 2024	-1.8x	P/E 2025	0.33x
Enterprise Value	-4.45M -3.83M -3.59M -3.28M -6.18M -425M -6.2M -42.63M -16.63M -215M -16.7M -16.33M -711M	EV / Sales 2024	0.34x	EV / Sales 2025	-0.84x
Free-Float	14.03%	Yield 2024 *	-	Yield 2025	-

May. 18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
Nov. 17	Adaptimmune Therapeutics plc Announces CEO Changes	CI
Nov. 17	Adaptimmune Therapeutics plc Announces Leadership Changes	CI
25-10-27	Evaxion Names Helen Tayton-Martin as Chief Executive Officer	MT
25-10-26	Adaptimmune Therapeutics plc(OTCPK:ADAP.Y) dropped from NASDAQ Composite Index	CI
25-10-24	European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading	MT
25-10-23	European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading	MT
25-10-22	European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading	MT
25-10-21	European Equities Traded in the US as American Depositary Receipts Decline in Tuesday Trading	MT
25-10-20	Top Midday Decliners	MT
25-10-20	European Equities Close Mostly Higher in Monday Trading; UK Sentiment Sees 'Some of the Gloom Lift'	MT
25-10-20	European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading	MT
25-10-20	Adaptimmune Therapeutics to Voluntarily Delist From Nasdaq	MT

25-07-30	Guggenheim Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-07-29	HC Wainwright Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-06-26	Mizuho Downgrades Adaptimmune Therapeutics to Neutral From Outperform, Cuts Price Target to $0.50 From $1.50 on Solvency Concerns	MT
24-11-27	Mizuho Cuts Price Target on Adaptimmune Therapeutics to $1.50 From $3, Keeps Outperform Rating	MT
24-07-30	HC Wainwright Starts Adaptimmune Therapeutics With Buy Rating, $4 Price Target	MT

Adaptimmune Therapeutics plc Stock Börse Stuttgart

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US00653A1079

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Nov. 17	Adaptimmune Announces Changes to Board and Executive Leadership Team	NE
25-10-20	Adaptimmune Announces Delisting from Nasdaq	NE
25-08-13	Adaptimmune Reports Q2 Financial Results and Provides Business Update	NE
25-07-28	Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds	NE
25-05-13	Adaptimmune Reports Q1 Financial Results and Provides Business Update	NE

24-05-30	Galapagos gaat samenwerken met Adaptimmune
24-04-12	Roche: Genentech met fin à la collaboration avec Adaptimmune Therapeutics
24-04-12	Roche-Tochter Genentech beendet Zusammenarbeit mit Adaptimmune Therapeutics
23-04-11	GSK : Adaptimmune reprend les droits de deux programmes
21-09-07	Aktien Schweiz Schluss: SMI unter Druck

Manager	Title	Age	Since
Christopher Hill CEO	Chief Executive Officer	46	2025-11-13
Juli P. Miller IRC	Investor Relations Contact	-	2016-07-31
Phil Bassett PRN	Corporate Officer/Principal	-	-

Director	Title	Age	Since
Lawrence Alleva CHM	Chairman	76	2025-11-13
Garry Menzel BRD	Director/Board Member	61	2023-05-31
Christopher Hill BRD	Director/Board Member	46	2025-11-13

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Average	-2.17%	-1.20%	+58.49%	+46.49%	43.29B
Weighted average by Cap.	-2.42%	-2.05%	+83.84%	+41.75%

	2024	2025
Net sales	178M 153M 144M 131M 247M 17.02B 248M 1.71B 666M 8.59B 668M 654M 28.48B	5.92M 5.1M 4.79M 4.37M 8.23M 566M 8.26M 56.78M 22.16M 286M 22.24M 21.76M 948M
Net income	-70.81M -61.02M -57.21M -52.23M -98.39M -6.77B -98.7M -679M -265M -3.42B -266M -260M -11.33B	25.21M 21.72M 20.36M 18.59M 35.02M 2.41B 35.13M 242M 94.27M 1.22B 94.64M 92.58M 4.03B
Net Debt	-77.4M -66.69M -62.53M -57.08M -108M -7.4B -108M -742M -289M -3.73B -291M -284M -12.38B	-11.87M -10.23M -9.59M -8.75M -16.49M -1.13B -16.54M -114M -44.39M -573M -44.56M -43.59M -1.9B

1 week	-41.18%
6 months	-68.75%
Current year	-9.09%

1 week	0.01	0.02
1 month	0	0.02
3 years	0	1.64
5 years	0	5.6