Lilly Diabetes & Obesity

ADA Update

June 7, 2022

SAFE HARBOR PROVISION

This presentation contains forward-looking statements that are based on management's current expectations, but actual results may differ materially due to various factors. The company's results may be affected by factors including, but not limited to, the risks and uncertainties in pharmaceutical research and development; competitive developments; regulatory actions; the extent and duration of the effects of the COVID-19 pandemic; litigation and investigations; business development transactions; economic conditions; and changes in laws and regulations, including health care reform.

For additional information about the factors that affect the company's business, please see the company's latest Form 10-K and subsequent filings with the Securities and Exchange Commission.

The company undertakes no duty to update forward-looking statements

except as required by applicable law

Not for promotional use

2022 LILLY ADA UPDATE

2

Introduction

Mike Mason, President, Lilly Diabetes

Tirzepatide SURMOUNT-1 Phase 3 Results & New Insights

Jeff Emmick, M.D., Ph.D., Vice President, Lilly Diabetes

Agenda

Product Development

Early Phase ADA Highlights & Portfolio Overview

Ruth Gimeno, Ph.D., Vice President, Lilly Diabetes and

Metabolic Research

Q&A

MOUNJAROTM NOW APPROVED IN THE U.S. FOR T2D

FIRST AND ONLY GIP AND GLP-1 RECEPTOR AGONIST AVAILABLE FOR PATIENTS

Delivered superior A1C reductions versus all comparators in Phase 3 SURPASS clinical trials

Although not indicated for weight loss, led to significantly greater weight reductions versus comparators in a key secondary endpoint

Shipments to wholesalers are underway and pharmacies will begin to see supply as prescriptions are written

Enabling new patient starts through patient support programs as we work to build broad access:

  1. 1 month sample (4 weeks) of starting 2.5 mg pens prior to HCP writing a 5 mg prescription
  1. Copay program with out-of-pocket costs as little as $25 per month for eligible commercially insured patients

T2D=type 2 diabetes; HCP=healthcare professional

Not for promotional use

2022 LILLY ADA UPDATE

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INNOVATION DRIVES EXPANDED STRATEGIC FOCUS

DIABETES AND OBESITY

OUR FOUNDATION

People

with

Diabetes

+

Improving and simplifying

glycemic control

OUR EXPANDED FOCUS

Obesity Diabetes

+

Disrupting disease progression in

Diabetes & Obesity to improve outcomes

Not for promotional use

2022 LILLY ADA UPDATE

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Eli Lilly and Company published this content on 07 June 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 07 June 2022 13:11:07 UTC.