On June 16, 2021, Enrique Carrazana provided notice of his resignation as a member of the Board of Directors of Marinus Pharmaceuticals, Inc. effective as of June 30, 2021. Mr. Carrazana served as a member of the Compensation Committee of the Board. The Board appointed Sara Nochur to the Compensation Committee, also effective as of June 30, 2021. Further, the size of the Board was reduced from nine to eight directors, also effective as of June 30, 2021. Mr. Carrazana's resignation from the Board was not due to any disagreement with the Company on any matter relating to the Company's operations, policies or practices.