MedinCell announced that its partner, Arthritis Innovation Corporation (AIC), who conducts and finances all development activities of F14 (MedinCell codename: mdc-CWM), has registered its multicenter, randomized, double blind Phase 3 safety and efficacy study on the public trials registry, clinicaltrials.gov. Enrollment of first patients is expected this month. F14 (mdc-CWM) is a sustained-release formulation of the non-steroidal anti-inflammatory drug (NSAID), celecoxib, designed to reduce pain and inflammation and enhance recovery after TKR.

F14 (mdc-CWM) is administered into the intra-articular space at the end of TKR surgery and may provide pain relief over several weeks post-surgery.