OptimizeRx : Corporate Presentation

Technology Solutions For Life Sciences at the Point-of-Care

Corporate Presentation

Physician

Awareness

Digital Therapy	Patient
Initiation	Adherence

Our Mission

At OptimizeRx ― we are building a more informed and empowered healthcare community by developing new technology solutions that help people start and stay on life-impacting therapies.

Growth Leaders | Growth Drivers

EXPERIENCE	EXPERIENCE	EXPERIENCE
20+	20+	20+
Leading Health Services and	Senior Financial	Operations, Sales,
Financial Businesses	Roles	and Growing
		Partner Networks

Will Febbo	Ed Stelmakh	Steve Silvestro
Chief Executive Officer	Chief Financial Officer /	Chief Commercial Officer
	Chief Operations Officer

EXPERIENCE	EXPERIENCE
30+	20+
Healthcare IT,	Legal
Master Data Mgmt	Corporate and Business
	Compliance

Todd Inman	Marion Odence-Ford
Chief Technology Officer	General Counsel & Chief Compliance Officer

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At-a-Glance

A leading provider of point-of-care technology solutions helping patients start and stay on therapy

Corporate Profile

• Re-Foundedin 2016, OptimizeRx enables engagement between life sciences organizations, physicians and patients
• OptimizeRx powers drug maker brand awareness with physicians as well as patient treatment initiation, affordability and adherence efforts
• Our technology platform coupled with the nation's largest patient point-of-carenetwork connects the majority of U.S. physicians and millions of patients
• The Company has grown to ~110 employees across the United States and Croatia

Stock Information

Stock Price	$14.23
(as of 4/4/23)
Shares Outstanding	~17.1M
fully diluted (as of 2/28/23)
Market Cap	~$243.3M
(as of 4/4/23)
Cash, Cash Equivalents1	$74.1M
(as of 12/31/22)
Total Debt	$0.00

NASDAQ Exchange listed under ticker

(NASDAQ:OPRX)

(1) Includes short-term investments

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Pharma is Facing New Problems… and Some Old Ones…

Increased Focus on Medical Science Liaisons

of KOLs perceive interactions with MSLs 76% to be more valuable than interactions

with drug sales reps

Script Abandonment

~50%	at the pharmacy(2)
	of patients never fill their scripts

Diagnosis Criteria Increasingly Complex

12M	People are affected by medical
diagnostic errors each year(3)

Shift to Specialty Medications

81%	of new drug approvals are
specialty medications(4)

Daily EHR Use Can Be All-Consuming

5.9	average daily EHR use by
hrs/day	HCPs(5)

Affordability

43-49%increase of total spend on specialty medications(6)

(1) ZS's 2017 AccessMonitor and AffinityMonitor Findings. (2) Center for Disease Control, "Prescription Medication Adherence" . (3) U.S Department of Veterans Affairs, "Twelve million patients misdiagnosed yearly in
America". (4) RxBenefits, "Don't Ignore the Growing Specialty Medication Trends. (5) Tethered to the EHR: Primary Care Physician Workload Assessment Using EHR Event Log Data and Time-Motion Observations. (6)	5
ASPE Office of Science & Data Policy, "Trends in Prescription Drug Spending, 2016-2021".