Item 8.01 Other Events.

On March 30, 2022, VYNE Therapeutics Inc. (the "Company") issued a press release entitled "VYNE Reports Positive Preclinical Data for Intra-Articular Injection of Pan-BET Inhibitor, VYN201, in an In Vivo Model of Rheumatoid Arthritis." A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein.

Item 9.01. Financial Statements and Exhibits.





(d) Exhibits

The following exhibit is being filed herewith.

Exhibit No. Description

99.1 Press Release, dated March 30, 2022.



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