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    AZN   GB0009895292

ASTRAZENECA PLC

(AZN)
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Canada Vaccine Panel Recommends Against AstraZeneca PLC for Second Dose

06/17/2021 | 04:05pm EDT

By Kim Mackrael

OTTAWA--A Canadian vaccine panel said Thursday that people who received a first dose of AstraZeneca PLC's vaccine against Covid-19 should get a different vaccine for their second dose.

Canada's national advisory panel on immunization said earlier this month that authorized Covid-19 vaccines could be mixed, and noted some people might prefer to get a messenger RNA vaccine for their second shot. The panel has previously said mRNA vaccines, such as the ones produced by Pfizer Inc. in partnership with BioNTech SE, as well as Moderna Inc., are preferable to viral vector vaccines, such as those developed by AstraZeneca and Johnson & Johnson.

On Thursday, it changed its advice to recommend against the use of AstraZeneca's vaccine in most cases.

"An mRNA vaccine should now be offered as the second dose for individuals who received a first dose" of AstraZeneca's vaccine, said Dr. Howard Njoo, Canada's deputy chief public health officer. People who are getting their first vaccine dose should also be offered an mRNA vaccine unless they have a contraindication or none of those vaccines are available, he said.

Dr. Njoo said the advisory panel's advice is based on emerging evidence that shows a potentially better immune response from a mixed vaccine schedule, and concerns about blood clotting associated with the AstraZeneca vaccine. Another factor the advisory panel considered is the increased availability of mRNA vaccines in Canada, he said.

The panel's recommendations aren't binding, but tend to be followed by provinces in Canada, which are responsible for delivering health care.

After a sluggish start earlier in the year, Canada has sharply increased its administration of Covid-19 vaccines in recent months. Nearly 66% of the population had received at least one dose of a Covid-19 vaccine as of June 16, although just 15% of the population is fully vaccinated.

Write to Kim Mackrael at kim.mackrael@wsj.com

(END) Dow Jones Newswires

06-17-21 1805ET

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Financials (USD)
Sales 2021 35 164 M - -
Net income 2021 5 236 M - -
Net Debt 2021 25 946 M - -
P/E ratio 2021 21,8x
Yield 2021 3,41%
Capitalization 128 B 178 B -
EV / Sales 2021 4,38x
EV / Sales 2022 3,53x
Nbr of Employees 76 100
Free-Float 96,4%
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Number of Analysts 29
Last Close Price 82,70 $
Average target price 133,83 $
Spread / Average Target 61,8%
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Managers and Directors
Pascal Soriot Chief Executive Officer & Executive Director
Marc Pierre Jean Dunoyer Chief Financial Officer & Executive Director
Leif Valdemar Johansson Non-Executive Chairman
Menelas N. Pangalos EVP-Biopharmaceuticals Research & Development
Pam P. Cheng Executive VP-Operations & Information Technology
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