Aralez Pharmaceuticals Inc. announced new data for YOSPRALA™, a recently FDA-approved prescription fixed-dose combination of aspirin, an anti-platelet agent, and omeprazole, a proton pump inhibitor (PPI), demonstrated significantly lower rates of gastric and duodenal ulcers compared to aspirin alone among patients with a history of myocardial infarction at risk for secondary cardiovascular events and gastrointestinal problems related to aspirin therapy at the annual American Heart Association Scientific Sessions. The study, titled "Efficacy and Safety of PA32540 (Enteric-Coated Aspirin 325 mg and Immediate-Release Omeprazole 40 mg) in Patients With a History of Myocardial Infarction: Analyses From Two Phase 3 Clinical Trials," found that YOSPRALA 325 mg /40 mg was associated with significantly lower rates of gastric ulceration compared to 325 mg of enteric-coated aspirin (2.3% vs 7.5%; p=0.020) in these patients. Treatment with YOSPRALA was also associated with lower rates of duodenal ulcers (2.3% vs 9.5%; p=0.002) compared to enteric-coated aspirin in this population. Safety results in this population were comparable with the entire study population.